AS AS Roma has officially announced its starting line-up for the highly anticipated Serie A clash against league leaders Inter, set to kick off at San Siro today, April 5, 2026, at 19:45 UK time (20:45 CEST). The Giallorossi welcome back key players Matias Soulé and Donyell Malen, aiming to challenge a Nerazzurri side that has recently shown signs of vulnerability.

Inter, despite holding a significant lead at the top of the table, has seen their advantage shrink from ten points to just six following a defeat to AC Milan and subsequent 1-1 draws against Atalanta and Fiorentina. This dip in form coincided with the absence of star striker Lautaro Martinez, who returns for this crucial fixture.

For Inter, Lautaro Martinez makes his first start since a calf strain sustained on February 18, partnering Marcus Thuram upfront. Hakan Calhanoglu has also recovered from a knock. However, coach Simone Inzaghi faces defensive adjustments, with Francesco Acerbi stepping in due to Yann Bisseck's injury and Carlos Augusto's suspension. Alessandro Bastoni will also feature in defence.

AS AS Roma's confirmed line-up sees the return of Matias Soulé and Donyell Malen, providing a significant boost to their attacking options as they prepare to face Inter. The team will be looking to exploit any lingering uncertainty in the Nerazzurri's defence and midfield, aiming for a vital away victory at the iconic Giuseppe Meazza Stadium.

This encounter holds immense importance for both clubs. Inter seeks to reassert their dominance and extend their lead, while AS AS Roma aims to capitalize on their opponent's recent struggles and climb higher in the Serie A standings. The tactical battle at San Siro promises to be a captivating affair, with both sides eager to secure three points.

Fans can follow all the build-up and live action from this pivotal Serie A match, along with other games scheduled for today, through dedicated liveblogs and sports coverage.